HEAL Initiative: Program to Reveal and Evaluate Cells-to-gene Information that Specify Intricacies, Origins and the Nature of (PRECISION) Human Pain Network
This grant will fund large-scale, collaborative research to generate and analyze comprehensive omics and physiology datasets from human pain tissues, advancing understanding of pain mechanisms.
Funder: National Institutes of Health
Due Dates (Anticipated): October 2026 (Full application deadline, projected)
Funding Amounts: Cooperative agreements; typical NIH multi-center awards range from several million dollars per year, duration varies by project.
Summary: Supports large-scale, high-throughput ‘omics and physiology data generation and analysis using primary human tissue to advance understanding of human pain mechanisms and build a collaborative research network.
Key Information: This is a forecasted opportunity; details may change and applications are not yet being accepted.
Description
This anticipated funding opportunity from the National Institutes of Health (NIH), under the HEAL (Helping to End Addiction Long-term) Initiative, will support comprehensive ‘omics and physiology dataset generation using primary human tissue across the pain neuraxis. The program seeks multidisciplinary teams to generate, analyze, and disseminate large-scale datasets of human genes, epigenome, transcriptome, proteome, metabolome, and phenotypes at the single-cell and tissue levels. Awardees will form a collaborative network to optimize protocols, replicate findings, and build an integrated knowledgebase to benefit the broader pain research and therapeutic development communities. The program will use a milestone-driven, cooperative agreement mechanism with active NIH program staff involvement to ensure alignment with HEAL data sharing priorities.
