Funder: National Institutes of Health
Due Dates: June 16, 2025 (New) | July 16, 2025 (Renewal/Resubmission/Revision) | September 7, 2025 (AIDS) | October 16, 2025 (New) | November 16, 2025 (Renewal/Resubmission/Revision) | January 7, 2026 (AIDS) | Additional standard NIH dates through January 7, 2028
Funding Amounts: Up to $50,000 direct costs per year, max 2 years (total $100,000 direct costs); no cost sharing required.
Summary: Supports research to identify, develop, or test strategies for overcoming barriers to the adoption, scale-up, and sustainability of evidence-based health interventions, including de-implementation of ineffective practices.
Key Information: Clinical trials are not allowed; all applications must align with the mission of a participating NIH Institute or Center.
Description
This NIH opportunity supports small research projects (R03 mechanism) focused on dissemination and implementation (D&I) science in health. The goal is to advance understanding and strategies for overcoming barriers to the adoption, adaptation, integration, scale-up, and sustainability of evidence-based interventions, practices, programs, tools, treatments, guidelines, and policies. Projects may also address the de-implementation of ineffective, unproven, low-value, or harmful practices.
Studies that promote equitable dissemination and implementation among underrepresented or underserved communities are encouraged. The program also welcomes research to advance D&I research methods and measures. All projects must be within the mission scope of at least one of the participating NIH Institutes or Centers.
Due Dates
- Standard NIH R03 due dates apply:
- June 16, 2025 (New applications)
- July 16, 2025 (Renewal/Resubmission/Revision)
- September 7, 2025 (AIDS-related applications)
- October 16, 2025 (New)
- November 16, 2025 (Renewal/Resubmission/Revision)
- January 7, 2026 (AIDS)
- Additional cycles continue through January 7, 2028
- Letter of Intent: 30 days prior to application due date (recommended, not required)
- All applications due by 5:00 PM local time of applicant organization
See the full NIH standard due dates here.
Funding Amount
- Direct costs: Up to $50,000 per year
- Project period: Maximum 2 years
- Total direct costs: Up to $100,000
- No cost sharing or matching required
- Indirect costs: As per institutional rates and NIH policy
Eligibility
Eligible applicants include:
- Public and private institutions of higher education (domestic and foreign)
- Nonprofits (with or without 501(c)(3) status)
- For-profit organizations (including small businesses)
- State, county, city, township, and special district governments
- Independent school districts
- Public housing authorities/Indian housing authorities
- Native American tribal governments and organizations (federally recognized and other)
- Faith-based and community-based organizations
- Regional organizations
- U.S. territories and possessions
- Non-domestic (non-U.S.) entities and components of U.S. organizations
Note: All applications must be within the mission of a participating NIH Institute or Center. Foreign organizations are eligible to apply.
Application Process
- Submission: Applications must be submitted electronically via Grants.gov, NIH ASSIST, or an institutional system-to-system solution.
- Required registrations: SAM, Grants.gov, eRA Commons, and (for foreign organizations) NCAGE code.
- Application format: Use the SF424 (R&R) forms and follow the NIH Research (R) Instructions here.
- Research Plan: Must address significance, innovation, approach, and expertise/resources as outlined in the FOA.
- Data Management and Sharing Plan: Required for all applications.
- Clinical trials: Not allowed under this FOA.
- Appendix: Only limited materials allowed (e.g., blank surveys).
Review criteria include significance, innovation, approach, investigator(s), and environment, with additional attention to D&I research principles and stakeholder engagement.
Additional Information
- Scope: Projects should be appropriate for the R03 mechanism—small, focused, and feasible within 2 years and the budget cap.
- Non-responsive applications: Proposals testing therapies, imaging, diagnostics, biologics, or devices (e.g., first-in-human studies or efficacy trials) are not allowed.
- Companion opportunities: Larger or more exploratory projects should consider the R21 (PAR-25-143 here) or R01 (PAR-25-144 here) mechanisms.
- Participating Institutes/Centers: Multiple NIH ICs participate; applicants are encouraged to contact program staff to ensure alignment with IC priorities.
- Data sharing: All applications must include a data management and sharing plan per NIH policy.
External Links
Contact Information
| Topic | Contact | Email | Phone |
|---|
| General Grants Info | NIH Grants Information | GrantsInfo@nih.gov | 301-480-7075 |
| Application Submission | eRA Service Desk | | 301-402-7469 / 866-504-9552 |
| Grants.gov Support | Grants.gov Customer Support | support@grants.gov | 800-518-4726 |
| Scientific/Research Contacts | See Section VII of the FOA here for a full list by Institute/Center | | |
| Financial/Grants Management | See Section VII of the FOA here for a full list by Institute/Center | | |
External Links