Developing novel theory and methods for understanding the genetic architecture of complex human traits (R01 Clinical Trial Not Allowed)
Funding available for developing new theories and methods to understand genetic influences on human traits using interdisciplinary approaches and large datasets.
Funder: National Institutes of Health
Due Dates: January 5, 2025 (Letter of Intent) | February 5, 2025 (New) | March 5, 2025 (Renewal/Resubmission/Revision) | June 5, 2025 (New) | July 5, 2025 (Renewal/Resubmission/Revision) | October 5, 2025 (New) | November 5, 2025 (Renewal/Resubmission/Revision) | February 5, 2026 (New) | March 5, 2026 (Renewal/Resubmission/Revision) | June 5, 2026 (New) | July 5, 2026 (Renewal/Resubmission/Revision) | October 5, 2026 (New) | November 5, 2026 (Renewal/Resubmission/Revision)
Funding Amounts: No budget cap for most applications; NCI applications limited to $350,000 direct costs/year; project period up to 5 years.
Summary: Supports interdisciplinary research to develop novel theory and methods for understanding how genetic and non-genetic factors shape complex human traits using large-scale datasets.
Key Information: Clinical trials are not allowed; methods must be generalizable and not focused solely on specific traits or data generation.
Description
This opportunity supports the development of innovative theories and methods to better understand the genetic architecture of complex human traits. The focus is on integrating genetic and non-genetic factors—such as environmental, social, and ecological influences—across individuals, families, and populations. Projects should be interdisciplinary, drawing from both natural and social sciences, and should leverage large-scale, publicly available datasets for modeling and empirical validation. The aim is to move beyond traditional, reductionist approaches and develop comprehensive frameworks that account for the complexity and interdependencies influencing human traits.
