Shared Instrumentation Grant (SIG) Program (S10 Clinical Trial Not Allowed)
A grant program that supports NIH-funded groups in purchasing high-priced, specialized scientific instruments, offering awards from $50,000 to $750,000 with no set maximum instrument price.
Funder: National Institutes of Health
Due Dates: June 2, 2025 | June 1, 2026 | June 1, 2027 (New, Renewal, Resubmission, Revision)
Funding Amounts: $50,000–$750,000 per award (one-year project period; no maximum instrument price, but NIH award capped at $750,000)
Summary: Supports NIH-funded groups in acquiring or upgrading a single, high-cost, specialized research instrument for shared use in biomedical research.
Key Information: At least three NIH-funded major users required; only one instrument per application; clinical trials not allowed.
Description
The Shared Instrumentation Grant (SIG) Program provides funding to purchase or upgrade a single, high-priced, specialized, commercially available research instrument or integrated instrumentation system. The program is designed to enhance the research capabilities of groups of NIH-supported investigators by enabling access to state-of-the-art equipment that is otherwise unaffordable for individual labs. Instruments must be dedicated to research use only and are expected to be housed in a core facility or shared resource to maximize access and impact.
Supported instruments include, but are not limited to:
- Light and electron microscopes
- Biomedical imagers
- Mass spectrometers
- Nuclear magnetic resonance (NMR) spectrometers
- Flow cytometers
- DNA and protein sequencers
- Biosensors
- X-ray diffractometers
Standalone computer systems are eligible only if dedicated solely to biomedical research.
