Funder: National Institutes of Health
Due Dates: November 5, 2026 (Renewal / Resubmission / Revision) | February 5, 2027 (New) | March 5, 2027 (Renewal / Resubmission / Revision) | June 5, 2027 (New) | July 5, 2027 (Renewal / Resubmission / Revision) | October 5, 2027 (New) | November 5, 2027 (Renewal / Resubmission / Revision) | January 7, 2028 (Closing date)
Funding Amounts: No budget cap; requests must reflect project needs; up to 5 years, generally 4 years for non-ESIs
Summary: Supports NIGMS-relevant technology development from demonstrated proof of concept to validated working prototypes with broad biomedical research utility.
Key Information: Aims addressing specific biological questions are withdrawn without review; clinical trials are not allowed.
Description
The National Institute of General Medical Sciences (NIGMS), part of NIH, supports focused development of innovative technologies that enable acquisition of biomedical knowledge. This R01 opportunity targets technologies supported by proof-of-concept and preliminary data but facing substantial technical hurdles before a working prototype can be developed and validated.
Projects may develop laboratory instruments and devices, algorithms and software, chemical reagents and processes, or human-modified biological molecules and systems used as research tools. The goal is a significant advance over existing capabilities, characterized sufficiently for future application to a broad range of biomedical questions. Validation may use well-characterized test systems or known standards, but the project must focus entirely on technology development rather than generating new biological knowledge.
