High-End Instrumentation (HEI) Grant Program (S10 Clinical Trial Not Allowed)
HEI Grant Program allows NIH-funded groups to buy high-end instruments ($750k-$2M) like microscopes, sequencers, and spectrometers.
Funder: National Institutes of Health
Due Dates: June 2, 2025 (New, Renewal, Resubmission, Revision) | June 1, 2026 | June 1, 2027
Funding Amounts: $750,001 minimum; up to $2,000,000 for a single high-end instrument; one-year award period.
Summary: Supports NIH-funded groups to purchase or upgrade a single high-end, specialized, commercially available instrument or integrated system for biomedical research.
Key Information: Updated March 31, 2025: Carefully review the full announcement for recent changes and agency priorities.
Description
This program provides funding for the purchase or upgrade of a single high-end, specialized, commercially available instrument or integrated system to support NIH-funded research. The goal is to make advanced research instrumentation available to groups of NIH-supported investigators, enabling cutting-edge basic, translational, and clinical biomedical or biobehavioral research that would not be possible otherwise. Supported instruments include, but are not limited to, nuclear magnetic resonance spectrometers, X-ray diffractometers, mass spectrometers, high-throughput robotic screening systems, DNA and protein sequencers, biosensors, electron and light microscopes, flow cytometers, and biomedical imagers.
The program is administered by the NIH Office of Research Infrastructure Programs (ORIP), with participation from NIBIB and NIGMS. Instruments must be dedicated to biomedical research and justified on a shared-use basis.
