HIV Prevention and Alcohol (R01 Clinical Trials Optional)
This grant aims to enhance HIV prevention strategies in populations affected by alcohol use through research in diverse settings focusing on interventions, prevention, and treatment.
Funder: National Institutes of Health
Due Dates: September 7, 2025 (AIDS) | January 7, 2026 (AIDS) | May 7, 2026 (AIDS)
Funding Amounts: Estimated 2–4 awards; total of $2M in FY25; no budget cap, up to 5 years/project.
Summary: Supports research to expand HIV prevention strategies among alcohol-impacted populations, including intervention development, implementation, and integration.
Key Information: Clinical trials are optional; foreign and domestic applicants eligible; contact NIH if requesting ≥$500K direct costs/year.
Description
This opportunity from the National Institutes of Health (NIH), led by the National Institute on Alcohol Abuse and Alcoholism (NIAAA), seeks to expand the HIV/AIDS prevention toolkit for populations impacted by alcohol use. The focus is on research that addresses the behavioral and biological risks for HIV acquisition associated with episodic and long-term alcohol use, including mental health and substance use comorbidities.
The program supports the development, testing, and implementation of new or expanded interventions, as well as integration of effective prevention and treatment strategies in diverse settings and populations. Six primary research areas are emphasized:
- PrEP Utilization
- Treatment as Prevention (TasP)
- Integration of Preventive Intervention Strategies
- Prevention-related Cross-cutting Research
- Syndemic Approaches
- Implementation and Operations Research
Projects may include laboratory, clinical, epidemiological, and intervention studies, and may propose clinical trials (optional). Research should address high-risk groups (e.g., MSM, sex workers, serodiscordant couples, women with high-risk partners, individuals in HIV “hot spots,” etc.) and may incorporate innovative technologies, measurement, and analytic approaches.
