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    Immune Profiling Insights Program

    This grant funds research using existing biosamples to uncover immune mechanisms that drive Parkinson’s disease risk, onset, and progression, integrating immune profiling with biomarker and clinical data.

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    Funder: Aligning Science Across Parkinson's

    Due Dates: May 15, 2026: Full proposal submission deadline

    Funding Amounts: Total program budget: $3M | Typical award duration: 6–24 months | Budgets should be commensurate with proposed work

    Summary: Supports research using existing biosamples to uncover immune mechanisms contributing to Parkinson’s disease risk, onset, and progression.

    Key Information: Postdoctoral fellows are not eligible as PIs; collaboration and prior biosample access required.


    Description

    The Immune Profiling Insights Program, led by The Michael J. Fox Foundation for Parkinson’s Research in partnership with Aligning Science Across Parkinson's (ASAP), funds hypothesis-driven research to clarify how specific immune system components influence Parkinson’s disease (PD) risk, onset, and progression. The program aims to identify immune cell populations, signaling pathways, and functional states that change across the PD continuum, and to link these findings to clinical heterogeneity and disease trajectory. Research should leverage validated immunophenotyping and functional assays on existing, well-characterized biosamples from PD cohorts, integrating immune data with established or emerging PD biomarkers.


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