[Aligning Science Across Parkinson's](https://parkinsonsroadmap.org)

May 15, 2026: Full proposal submission deadline

Up to $3M total program funding; individual project budgets should be commensurate with proposed work (6–24 months duration).

Supports research to advance understanding of immune system mechanisms in Parkinson’s disease risk, onset, and progression.

--- ## Description The Immune Profiling Insights Program, offered by Aligning Science Across Parkinson’s (ASAP) in partnership with The Michael J. Fox Foundation for Parkinson’s Research, funds research that deepens scientific understanding of how specific components of the immune system influence Parkinson’s disease (PD). The program aims to identify immune cell populations, pathways, and functional states altered across the PD continuum, and to clarify how these features relate to clinical heterogeneity and disease trajectory. Projects are expected to use validated immunophenotyping and functional immune assays on banked biosamples from well-characterized PD cohorts, integrating results with existing clinical and biomarker data to uncover actionable insights for diagnosis, prevention, and treatment. --- ## Due Dates - May 15, 2026: Full proposal submission deadline (5 p.m. US ET) --- ## Funding Amount - Total program budget: Up to $3,000,000 - Project budgets: Should be commensurate with the proposed work - Project duration: 6 to 24 months - Indirect cost caps: 15% for academic/non-profit, 10% for for-profit institutions --- ## Eligibility - Open to researchers or clinicians at: - U.S. and non-U.S. biotechnology/pharmaceutical companies (public or private) - U.S. and non-U.S. public and private non-profit entities (universities, colleges, hospitals, labs, government units) - Postdoctoral fellows are **not eligible** to apply as Principal Investigators - Applicants must have established collaborations for access to required biosamples prior to submission; a letter of support from the biobank is required --- ## Application Process 1. Review the [RFA Overview](https://www.michaeljfox.org/sites/default/files/media/document/2026%20Immune%20RFA%20Overview_0.pdf) for detailed program priorities and requirements. 2. Prepare your proposal using the [Full Proposal Template](https://www.michaeljfox.org/sites/default/files/media/document/Immune%20RFA%20Full%20Proposal%20Template%202026.docx). 3. Secure a letter of support from the relevant biobank or cohort coordinator. 4. Submit your application via the [Grant Application Portal](https://grants.michaeljfox.org/s_Login.jsp) by May 15, 2026. 5. Ensure your application addresses diversity, equity, and inclusion (DEI) considerations, as well as MJFF’s Open Science Policy for sharing research outputs. --- ## Additional Information - Proposals **must** use existing biospecimen resources; prospective sample collection is not allowed. - The program prioritizes mechanistic, hypothesis-driven studies using validated immune assays on banked samples. - Proposals focused solely on developing new assays, large-scale untargeted discovery, or analysis of existing datasets are out of scope. - Projects must comply with [MJFF's Open Science Policy](https://doi.org/10.5281/zenodo.18778011), requiring open sharing of research outputs. - For questions about project fit or application requirements, email [grants@michaeljfox.org](mailto:grants@michaeljfox.org). --- ## External Links - [Program Overview and Application Instructions](https://www.michaeljfox.org/sites/default/files/media/document/2026%20Immune%20RFA%20Overview_0.pdf) - [Full Proposal Template](https://www.michaeljfox.org/sites/default/files/media/document/Immune%20RFA%20Full%20Proposal%20Template%202026.docx) - [Grant Application Portal](https://grants.michaeljfox.org/s_Login.jsp) - [Funding Opportunity Page (ASAP)](https://parkinsonsroadmap.org/funding-opportunities/#https://www.michaeljfox.org/grant/immune-profiling-insights-program) - [Funding Opportunity Page (MJFF)](https://www.michaeljfox.org/grant/immune-profiling-insights-program) - [ASAP Funding Opportunities](https://parkinsonsroadmap.org/funding-opportunities/) - [MJFF Open Science Policy](https://doi.org/10.5281/zenodo.18778011) --- ## Contact Information | Purpose | Contact Email | |-----------------------------------------------|---------------------------------------| | General program/application questions | [grants@michaeljfox.org](mailto:grants@michaeljfox.org) | | Open Science Policy questions | [openscience@michaeljfox.org](mailto:openscience@michaeljfox.org) | | ASAP general contact | [Contact Form](https://parkinsonsroadmap.org/contact-us/) |

Immune Profiling Insights Program

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