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    Immune Profiling Insights Program

    Funds research using immune profiling to uncover how immune system changes affect Parkinson’s disease risk, progression, and clinical outcomes, aiming to guide future therapies.

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    Funder: Michael J. Fox Foundation for Parkinson's Research

    Due Dates (Anticipated): October 2026 (Full application deadline, projected)

    Funding Amounts: Typical award size not specified; funding supports hypothesis-driven immune profiling research in Parkinson's disease.

    Summary: Supports research to clarify how immune system changes drive Parkinson’s disease progression and clinical outcomes.

    Key Information: All research outputs must comply with MJFF’s Open Science Policy (open access, data/code sharing).


    Description

    The program funds hypothesis-driven research to advance understanding of how specific immune system components contribute to Parkinson’s disease (PD) risk, onset, and progression. Emphasis is on identifying immune cell populations, signaling pathways, and functional states that change across the PD continuum, and on linking these immune features to clinical outcomes and disease progression. The aim is to inform future therapeutic strategies and patient selection for clinical studies. Research must leverage validated immunophenotyping and functional assays on existing biosamples and integrate immune data with established and emerging PD biomarkers. Collaborations that provide access to diverse, well-characterized PD cohorts are encouraged.


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