PCORI updated the guidelines to clarify that patient care costs are generally not covered, while dedicated funds for partner compensation and engagement activities are explicitly required. The update also confirms that unfunded applications may be resubmitted. Finally, specific scientific leads (Drs. Alex Uzdavines and Jinghua Ou) have been added to the contact section for any programmatic questions.
Funder: Patient-Centered Outcomes Research Institute
Due Dates (Anticipated): May 2026 (Letter of Intent) | September 2026 (Full application)
Funding Amounts: Up to $750,000 in direct costs per project; maximum project period is 3 years; total funds available up to ~$12 million per cycle.
Summary: Supports research to improve methods in patient-centered comparative clinical effectiveness research, focusing on AI, study design, data networks, and ethics.
Key Information: Individuals may not apply; only organizations are eligible. Engagement of patients and stakeholders is required.