Funder: Patient-Centered Outcomes Research Institute (PCORI)

Due Dates: May 13, 2025 (LOI) | September 3, 2025 (Full Application)

Funding Amounts: Up to $750,000 total direct costs over up to 3 years; $12 million available for this cycle.

Summary: Supports research to address high-priority methodological gaps in patient-centered comparative clinical effectiveness research (CER), with a focus on AI/ML, study design, data networks, and ethics.

Key Information: Letter of Intent required; addressing one of four program priorities is mandatory for responsiveness.