[U.S. National Science Foundation](https://www.nsf.gov/)

Proposals accepted anytime

$300,000–$800,000 per award (typical), up to $10M total program funding; awards generally for 2–3 years

Supports innovative research in biological informatics, instrumentation, and multidisciplinary infrastructure to advance basic biological research.

--- ## Description This opportunity supports pioneering research and development of infrastructure for biological research, focusing on innovative approaches in biological informatics, instrumentation, and multidisciplinary solutions. The program is designed to enable new capabilities for acquiring, managing, analyzing, and sharing biological data, or for developing novel instrumentation and associated methods that advance the field. Projects should demonstrate the potential to transform research in biology, particularly in areas supported by the NSF Directorate for Biological Sciences. The program encourages high-risk, high-reward proposals and multidisciplinary collaborations, including those that integrate across levels of biological organization. --- ## Due Dates - Proposals are accepted at any time; there is no fixed deadline. --- ## Funding Amount - Typical award size: $300,000 to $800,000 - Award duration: Generally 2–3 years - Estimated total program funding: $10,000,000 - Expected number of awards: up to 40 - No cost-sharing or matching required --- ## Eligibility - **Institutions of Higher Education:** Two- and four-year accredited U.S. institutions (including community colleges), acting on behalf of their faculty. - **Non-profit, Non-academic Organizations:** Independent museums, observatories, research laboratories, professional societies, and similar organizations in the U.S. directly associated with educational or research activities. - **International Branch Campuses:** Proposals involving international branches of U.S. institutions must justify the need for activities to occur at the branch rather than the U.S. campus. - **Principal Investigators:** No restrictions or limits on who may serve as PI or co-PI. --- ## Application Process - Proposals may be submitted via [NSF FastLane](https://www.fastlane.nsf.gov/), [Research.gov](https://www.research.gov/), or [Grants.gov](https://www.grants.gov/). - Follow the [NSF Proposal & Award Policies & Procedures Guide (PAPPG)](https://www.nsf.gov/publications/pub_summ.jsp?ods_key=pappg) for proposal preparation. - Letters of Intent and preliminary proposals are not required. - Proposals should be prefixed in the title according to the targeted theme (e.g., "IIBR Informatics:", "IIBR Instrumentation:", "IIBR Multidisciplinary:"). - Proposals must include a Project Summary (with keywords), Project Description (max 15 pages), Budget, Facilities statement, Data Management Plan, and other required NSF documents. --- ## Additional Information - The program is especially interested in projects that: - Develop new informatics tools or theoretical approaches for complex biological data. - Create or significantly improve instrumentation for biological research. - Offer multidisciplinary solutions integrating informatics and instrumentation. - Address the "Rules of Life" track, which seeks integrative research across biological scales. - No limits on the number of proposals per PI, co-PI, or organization. - All fields of science supported by the NSF Directorate for Biological Sciences are eligible, but projects focused on disease, clinical, or drug design research are not eligible. - Proposals must include plans for broader impacts, including education, outreach, and broadening participation. --- ## External Links - [NSF Program Page](https://www.nsf.gov/funding/opportunities/innovation-infrastructure-innovation-biological-research) - [Full Program Solicitation (PDF)](https://nsf-gov-resources.nsf.gov/solicitations/pubs/2018/nsf18595/nsf18595.pdf?VersionId=xFoupeWj4yc0VIKv.2d8_hBeis7ZOFBK) - [NSF Proposal & Award Policies & Procedures Guide](https://www.nsf.gov/publications/pub_summ.jsp?ods_key=pappg) - [Grants.gov Opportunity Listing](https://www.grants.gov/search-results-detail/359587) - [NSF Directorate for Biological Sciences](https://www.nsf.gov/bio/) --- ## Contact Information | Name | Email | Phone | |------------------------|-----------------------------------------|-----------------| | Robert Fleischmann | [rfleisch@nsf.gov](mailto:rfleisch@nsf.gov) | (703) 292-7191 | | Steve Ellis | [stellis@nsf.gov](mailto:stellis@nsf.gov) | (703) 292-7876 | | Jean X. Gao | [jgao@nsf.gov](mailto:jgao@nsf.gov) | (703) 292-7253 | | Peter H. McCartney | [pmccartn@nsf.gov](mailto:pmccartn@nsf.gov) | (703) 292-8470 | | NSF Grants.gov Support | [grantsgovsupport@nsf.gov](mailto:grantsgovsupport@nsf.gov) | | For technical questions regarding proposal submission, contact the FastLane and Research.gov Help Desk at 1-800-673-6188 or [fastlane@nsf.gov](mailto:fastlane@nsf.gov), [rgov@nsf.gov](mailto:rgov@nsf.gov). For Grants.gov support, call 1-800-518-4726 or email [support@grants.gov](mailto:support@grants.gov).

Infrastructure Innovation for Biological Research

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