Intervention Research to Improve Native American Health (R01 Clinical Trial Optional)
This grant funds research projects aimed at developing and testing interventions to improve health outcomes among Native American populations.
Funder: National Institutes of Health
Due Dates: October 21, 2025 | January 7, 2026 (AIDS) | October 21, 2026 | January 7, 2027 (AIDS)
Funding Amounts: No set budget limit; typical project period up to 5 years; $500,000+ direct costs/year require pre-approval.
Summary: Supports intervention research to improve health in Native American, Alaska Native, and Native Hawaiian communities, including development, adaptation, testing, and implementation of culturally appropriate health interventions.
Key Information: Community-engaged, culturally grounded approaches are required; strong evidence of tribal/community partnership and support is essential.
Description
This funding opportunity supports research projects aimed at improving health among Native American, Alaska Native, and Native Hawaiian populations. The program seeks to fund intervention research—including etiologic studies that inform intervention development, the development or testing of interventions for health promotion, prevention, treatment, or recovery, and dissemination/implementation research to overcome barriers to the adoption and sustainability of effective interventions.
Projects must be community-engaged, culturally appropriate, and designed for sustainability and potential scalability. Partnerships with Native communities are required at all stages, and projects should build on community strengths, knowledge, and resilience. Interventions may address individual behaviors, social or environmental determinants, or multi-level approaches.
The initiative is part of the NIH's broader effort to reduce health disparities and improve health equity among Native populations by supporting rigorous, community-driven research.
