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    Intramural - Extramural Collaboration for Advanced 3-D Tissue Models for Drug Screening (Clinical Trial Not Allowed)

    This grant funds collaborations to develop and validate advanced 3-D tissue models for drug screening, using NCATS bioprinting resources, to improve drug discovery without animal testing.

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    Funder: National Institutes of Health

    Due Dates: June 16, 2026 (Forecasted)

    Funding Amounts: Estimated total program funding: $1,600,000 | Expected number of awards: 2

    Summary: Supports development, validation, and demonstration of advanced 3-D tissue models for drug screening to accelerate therapeutic discovery.

    Key Information: Applicants must use NCATS 3-D Bioprinting laboratory resources; clinical trials are not allowed.


    Description

    This funding opportunity will support projects that develop, validate, and demonstrate advanced 3-D tissue models for drug screening. The goal is to create non-animal models that closely mimic tissue properties relevant to drug action, thereby improving predictive accuracy in drug development. Models should be robust, reliable, and suitable for high-throughput screening. This initiative expands on previous programs focused on 3-D skin and other tissue models, and requires applicants to utilize the expertise and infrastructure of the NCATS 3-D Bioprinting laboratory. The models should balance physiological relevance with practicality for drug screening applications.


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