[National Institutes of Health (NIH)](https://www.nih.gov/)

October 5, 2026 (estimated)

Estimated total program funding: $6,000,000; ~7 awards anticipated; 5-year project period.

Supports collaborative research sites to interrogate human kidney biopsy tissue and advance understanding of chronic and acute kidney diseases.

Forecasted opportunity; all dates and details are subject to change.

--- ## Description The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) intends to continue the Kidney Precision Medicine Project (KPMP), a major initiative aimed at improving understanding of chronic kidney diseases (CKDs) and acute kidney injuries (AKIs) through the collection and in-depth molecular interrogation of human kidney biopsy tissue. The project seeks to identify novel molecular pathways, targets, and disease subgroups by leveraging state-of-the-art methodologies and data analysis. This renewal will support: - Ongoing follow-up of existing KPMP participants (~500), - Enrollment and molecular interrogation of new participants (>500), - Collaborative data analysis and sharing across the research community. The funding mechanism includes a single U24 award for clinical/data coordination and up to 14 U01 awards for recruitment and tissue interrogation sites. All funded sites are expected to work collaboratively to achieve the scientific objectives of the KPMP. --- ## Due Dates - Estimated application due date: October 5, 2026 *All dates are projected based on the annual cycle; check the program page for updates.* --- ## Funding Amount - Estimated total program funding: $6,000,000 - Approximately 7 awards anticipated - Project period: up to 5 years - Cooperative agreement mechanism (U01 and U24 activity codes) - No cost sharing or matching required --- ## Eligibility Eligible applicants include: - State, county, and local governments - Independent school districts - Public and private institutions of higher education - Native American tribal governments and organizations - Public housing authorities/Indian housing authorities - Nonprofits with 501(c)(3) status (excluding higher education institutions) - For-profit organizations (including small businesses) - Faith-based and community-based organizations - Regional organizations - Eligible federal agencies - U.S. territories and possessions - Non-domestic (non-U.S.) entities (foreign institutions) See the [grant listing](https://www.grants.gov/search-results-detail/359199) for full eligibility details. --- ## Application Process - This is a forecasted opportunity; the Notice of Funding Opportunity (NOFO) will be published at a later date. - Applications will be submitted via [Grants.gov](https://www.grants.gov/). - The NOFO will specify application instructions, review criteria, and required documentation. - Prospective applicants should monitor the [Grants.gov opportunity page](https://www.grants.gov/search-results-detail/359199) for updates. --- ## Additional Information - The KPMP is a collaborative, multi-site initiative; awardees are expected to participate in consortium activities, data sharing, and joint analyses. - Awards will be made as cooperative agreements, involving substantial NIH scientific and programmatic involvement. - Both recruitment and tissue interrogation site proposals are eligible. --- ## External Links - [NIH Main Website](https://www.nih.gov/) - [Grants.gov Opportunity Listing (NOT-DK-26-302)](https://www.grants.gov/search-results-detail/359199) --- ## Contact Information | Name | Email | Phone | Affiliation | |-----------------------|--------------------------------------|---------------|----------------------------------------------------------| | Debbie S. Gipson, MS, MD | [Debbie.Gipson@nih.gov](mailto:Debbie.Gipson@nih.gov) | 301-480-2268 | National Institute of Diabetes and Digestive and Kidney Diseases | ---

Kidney Precision Medicine Project Tissue Interrogation Sites

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