[National Institutes of Health](https://www.nih.gov)

August 15, 2025 (anticipated)

Estimated $1,835,051 per award; U24 cooperative agreement; duration and total number of awards TBD.

NIDDK intends to fund a center to manage data and provide scientific coordination for ongoing liver cirrhosis studies, including a cohort study and a clinical trial.

This is a Notice of Intent; applications are not yet being accepted.

--- ## Description The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) at the NIH plans to issue a limited competition funding opportunity for a Scientific and Data Coordination Center to support the Liver Cirrhosis Network. The Center will provide clinical study management, technical biostatistical support, data analysis, dissemination of findings, and ancillary analyses for two major ongoing studies: the Liver Cirrhosis Network Longitudinal Cohort Study and the RESCU clinical trial (Rosuvastatin Efficacy and Safety for Cirrhosis in the United States). This opportunity is intended to ensure completion of enrollment and robust data management for these studies, as well as to foster collaborative and translational research in liver disease. The award will use the U24 cooperative agreement mechanism. --- ## Due Dates - **Anticipated application due date:** August 15, 2025 (This is a forecasted opportunity; the official Notice of Funding Opportunity (NOFO) has not yet been published.) --- ## Funding Amount - **Estimated award:** $1,835,051 per award (subject to change in the final NOFO) - **Funding mechanism:** U24 Cooperative Agreement - **Project period:** To be specified in the forthcoming NOFO - **Number of awards:** Not specified --- ## Eligibility Eligible applicants are expected to include: - State, county, city, or township governments - Special district governments - Independent school districts - Public and State-controlled institutions of higher education - Federally recognized Native American tribal governments - Public housing authorities/Indian housing authorities - Native American tribal organizations (other than federally recognized tribal governments) - Nonprofits with or without 501(c)(3) status (excluding institutions of higher education) - Private institutions of higher education - For-profit organizations (including small businesses) Investigators with expertise in liver disease, clinical data management, biostatistics, and translational science are encouraged to consider applying. --- ## Application Process - This is a **Notice of Intent** only; applications are not being accepted at this time. - The official Notice of Funding Opportunity (NOFO) will be published at a later date, providing full application instructions and requirements. - Potential applicants are encouraged to begin developing collaborations and project concepts in anticipation of the NOFO release. --- ## Additional Information - The Center will be responsible for supporting the completion of enrollment and data management for both the longitudinal cohort and the RESCU clinical trial. - Collaborative and translational research approaches are encouraged. - The U24 mechanism involves substantial NIH programmatic involvement. --- ## External Links - [NIH Funder Home Page](https://www.nih.gov) - [Forecasted Opportunity Notice (NIH Grants Guide)](https://grants.nih.gov/grants/guide/notice-files/NOT-DK-26-309.html) _(link may be temporarily unavailable)_ --- ## Contact Information | Contact Type | Details | |--------------|---------| | NIH Main Line | 301-496-4000 | | NIH Contact Page | [Contact NIH](https://www.nih.gov/about-nih/contact-nih) | ---

Notice of Intent to Publish a Funding Opportunity Announcement for Liver Cirrhosis Network: Scientific and Data Coordination Center (U24 Clinical Trial Optional)

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