Longitude Prize on ALS
A multi-stage international challenge funding AI-driven research to discover and validate new therapeutic targets for ALS, aiming to accelerate breakthroughs in ALS treatment.
Funder: ALS Association
Due Dates: December 3, 2025 (Stage 1 application deadline) | April 1, 2028 (Stage 3 application closing month) | August 1, 2030 (Winner applications close)
Funding Amounts: Total prize fund: £7.5 million (~$10M USD) across multiple stages; Stage 1: £100,000/team (20 teams), Stage 2: £200,000/team (10 teams), Stage 3: £500,000/team (5 teams), Final winner: £1,000,000.
Summary: Multi-stage global challenge supporting AI-driven discovery and validation of new therapeutic targets for ALS, culminating in a major prize for the most promising approach.
Key Information: Applications are closed for Stage 1; future stages remain open only to teams progressing from earlier rounds.
Description
The Longitude Prize on ALS is a five-year, £7.5 million (~$10 million USD) international challenge designed to accelerate the discovery of effective treatments for amyotrophic lateral sclerosis (ALS) by incentivizing the use of artificial intelligence and advanced computational biology. The competition supports multidisciplinary teams as they identify, prioritize, and validate new therapeutic targets for ALS, with staged funding and expert support at each phase. The ultimate goal is to catalyze breakthroughs that could transform the landscape of ALS therapeutics.
