[Alzheimer's Research UK](https://www.alzheimersresearchuk.org/research)

October 2026 (Full application deadline, projected)

Up to £750,000 per project; flexible based on scientific need; up to 5 years.

Supports ambitious, high-impact research on the treatment, diagnosis, and prevention of dementia, including large-scale and translational projects.

Lead applicant must be based at a UK academic/research institution; international collaborators allowed.

--- ## Description This scheme funds intermediate to large-scale research projects that align with Alzheimer’s Research UK’s strategy, focusing on the treatment, diagnosis, and prevention of dementia. The grant encourages bold, ambitious, and high-impact ideas, including clinical and translational research that accelerates progress toward a cure. Funding is also available for "added value" sub-studies of existing or planned clinical trials, such as validating new biomarkers or outcome measures. The scheme is highly flexible in both cost and duration, aiming to support proposals driven by scientific opportunity rather than a fixed funding limit. --- ## Due Dates - October 2026 (anticipated/projected, full application deadline) *All dates are projected based on the annual cycle; check the program page for updates.* --- ## Funding Amount - Up to £750,000 per project. - Funding is flexible and based on the scientific need and nature of the research questions. - Project duration: up to 5 years. - No set minimum, but all costs must be fully justified. - Alzheimer’s Research UK does not cover indirect costs. --- ## Eligibility - **Lead applicant** must be based at a UK academic or research institution (university, hospital department, or Research Council-funded institute). - Applications may include co-applicants and advisors from outside the UK, including industry partners. - Lead applicant must have a contract (fixed-term or tenure) covering the proposed duration of the grant. If not tenured, a co-applicant with tenure is required. - Companies and SMEs cannot apply as lead applicants but can participate as co-applicants. - Applicants with >12 months remaining on an existing ARUK major award are not eligible. - Projects must align with ARUK’s remit: biomedical research into Alzheimer’s disease and other dementias (treatment, diagnosis, prevention). Care or service delivery research is not eligible. - Ethical approval (for clinical work) and/or Home Office licences (for animal work) must be obtained as applicable. --- ## Application Process - Applications are submitted via the [ARUK grant application portal](https://grants.alzheimersresearchuk.org/). - The scheme appears on the portal only when open for applications. - The process includes: - Triage by expert panel members. - External peer review. - Rebuttal opportunity for applicants to respond to reviewer comments. - Lived Experience Review for studies involving human volunteers. - Final review and discussion by the Grant Review Board, incorporating both scientific and lived experience perspectives. - Funding decisions are based solely on scientific merit, suitability for the scheme, and open competition. - Applicants are expected to familiarize themselves with [ARUK research guidelines and policies](https://alzheimersresearchuk.org/research/for-researchers/resources-and-information/research-guidelines-and-policies/). --- ## Additional Information - Funding can be used for salaries (excluding the lead applicant), experimental costs, equipment, travel, and networking. - The grant does not cover indirect costs. - Regular progress reporting is required for all funded projects. - For translational research (e.g., drug discovery), partnership with the [Drug Discovery Alliance](https://alzheimersresearchuk.org/research/for-researchers/research-opportunities/drug-discovery/) is encouraged. - See the [Eligibility Guidelines (PDF)](https://www.alzheimersresearchuk.org/wp-content/uploads/2025/09/ARUK-Grant-Scheme-Eligibility-Document-September-2025.pdf) for detailed requirements. --- ## External Links - [Major Projects Grant Scheme Page](https://www.alzheimersresearchuk.org/grants/major-project/) - [Grant Application Portal](https://grants.alzheimersresearchuk.org/) - [Eligibility Guidelines (PDF)](https://www.alzheimersresearchuk.org/wp-content/uploads/2025/09/ARUK-Grant-Scheme-Eligibility-Document-September-2025.pdf) - [Research Guidelines and Policies](https://alzheimersresearchuk.org/research/for-researchers/resources-and-information/research-guidelines-and-policies/) - [Application FAQs](https://www.alzheimersresearchuk.org/research/for-researchers/grant-schemes/application-faqs/) --- ## Contact Information | Contact | Details | |------------------------|--------------------------------------------------------------| | Email | research@alzheimersresearchuk.org | | Phone | 0300 111 5555 | | Researcher Resources | [Resources and Information](https://www.alzheimersresearchuk.org/research/for-researchers/resources-and-information/) | ---

Major Projects

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