This grant funds innovative, high-risk research on cognitive aging and memory loss in early-career faculty, excluding projects primarily focused on neurodegenerative diseases like Alzheimer’s.
Funder: American Federation for Aging Research
Due Dates: April 15, 2026 (Letter of Intent) | mid-August, 2026 (Full Application, by invitation) | October 1, 2026 (Award Start)
Funding Amounts: Up to two awards of $750,000 each over 3 years; max 10% indirect costs allowed.
Summary: Supports transformative research by advanced Assistant or early Associate Professors in cognitive aging and memory loss, emphasizing high-risk, high-gain projects in basic and clinical science.
Key Information: Projects primarily focused on neurodegenerative diseases (e.g., Alzheimer’s) are not eligible.
This program, jointly offered by the McKnight Brain Research Foundation and the American Federation for Aging Research, aims to identify and support emerging scientific leaders conducting innovative research in cognitive aging and age-related memory loss. The awards target advanced Assistant Professors and recently appointed Associate Professors in the U.S., providing substantial start-up support for high-risk, high-reward projects in both clinical translational research and basic biological mechanisms underlying cognitive aging. The expectation is for research to yield transformative discoveries, such as pilot clinical trials, proof-of-concept interventions, preclinical data, or mechanistic studies that could identify new treatment targets. Projects at the intersection of age-related cognitive changes and disease-related impairment may be considered if clearly relevant, but proposals primarily focused on neurodegenerative diseases like Alzheimer’s are not supported. Awardees are expected to attend annual scientific meetings to foster collaboration and knowledge exchange.