McKnight Neurobiology of Brain Disorders Award supports independent investigators studying brain injury and disease mechanisms to advance understanding, diagnosis, prevention, treatment, or cure.
Funder: McKnight Foundation
Due Dates: October 15, 2026, at 5 PM Central time (Application deadline)
Funding Amounts: Up to four awards of $100,000 per year for three years ($300,000 per award)
Summary: Supports independent investigators studying brain injury and disease mechanisms to translate basic neuroscience into advances in diagnosis, prevention, treatment, or cure.
Key Information: Applicants must be independent investigators at U.S. nonprofit research institutions with at least three years in tenured or tenure-track faculty positions.
The McKnight Foundation, through the McKnight Endowment Fund for Neuroscience, supports independent investigators researching mechanisms of brain injury and diseases related to the neurobiology of brain disorders. The award connects defined clinical problems with basic neuroscience research that can improve understanding of disease and lead to advances in diagnosis, prevention, treatment, or cure.
Proposals must identify a clinical problem, present specific scientific aims, and explain how knowledge and experience from basic research will advance understanding of the disorder. The program emphasizes novelty or disruptive potential. Applicants must also describe how they foster a laboratory environment where all members feel valued and supported, and address environmental contributions to brain disorders when applicable.