Miniaturization and Automation of Tissue Chip Systems (MATChS) (U43/U44 Clinical Trial Not Allowed)
This grant supports the development of miniaturized automated tissue chip systems for use in drug development and biomedical research, with a focus on higher throughput measures, on-line sensing, and reduced manual handling. Small businesses will work with the NIH to develop milestones and pathways to commercialization.
This grant is no longer accepting proposals
National Institutes of Health has archived this opportunity.
Funder: National Institutes of Health
Due Dates: November 17, 2025
Funding Amounts: Not specified; award amounts and duration vary by project
Summary: Supports small businesses developing automated, miniaturized tissue chip systems to advance biomedical research and drug development.
Key Information: Clinical trials are not allowed; only U.S. small businesses are eligible.
Description
This funding opportunity supports small businesses through the Small Business Innovation Research (SBIR) cooperative agreement mechanisms to develop miniaturized and automated tissue chip systems (MATChS). The goal is to enable the creation of tools and turnkey technologies for higher throughput, automated measurement with online sensing, rapid data acquisition, and analysis. The intent is to reduce manual handling and increase the availability of advanced tissue chip platforms for drug development and other biomedical research applications. Awardees will collaborate with NIH staff, develop milestones and benchmarks, and pursue commercialization pathways for their technologies.
