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    Mission Boost Grants (MBG)

    The ACS Mission Boost Grant funds translational cancer research to advance promising discoveries from preclinical stages into human testing and early clinical studies.

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    Funder: American Cancer Society

    Due Dates: June 1, 2026 | December 1, 2026

    Funding Amounts: Stage I: Up to $135,000/year (2 years max) plus 10% indirect, total $297,000; Stage II: Up to $545,000 (18 months) plus 10% indirect

    Summary: Supports innovative cancer research projects focused on translating discoveries to human testing, with two-stage funding for clinical-enabling work.

    Key Information: Applicants may only submit one MBG application per cycle and cannot submit RSG, DBG, or CSDG in the same cycle.


    Description

    Mission Boost Grants (MBG) are designed to accelerate the translation of promising cancer research findings into human testing. The program provides two stages of funding: Stage I supports projects that define clear milestones to reduce risks for new drugs, devices, or procedures prior to patient studies; Stage II supports testing these interventions in cancer patients. The MBG mechanism aims to bridge the gap between preclinical research and early clinical studies, offering resources for independent investigators to advance clinical-enabling research and bring innovative interventions closer to patient impact.


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