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    National Cancer Institute Program Project Applications for the Years 2023, 2024, and 2025 (P01 Clinical Trial Optional)

    Apply for the National Cancer Institute's Program Project grant to fund investigator-initiated research projects on various areas of cancer research, such as biology, prevention, diagnosis, treatment, and control, with a requirement of at least three research projects and an Administrative Core.

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    Funder: National Institutes of Health

    Due Dates: January 25, 2026 | May 7, 2026 (AIDS) | May 26, 2026 (Current closing date) | April 7, 2026 (Next LOI for AIDS)

    Funding Amounts: No budget cap; budgets must reflect actual project needs; maximum project period is 5 years.

    Summary: Supports multi-project, integrated research programs in any area of cancer research, requiring at least three projects and an administrative core.

    Key Information: Letter of Intent requested 30 days before application; clinical trials optional.


    Description

    This opportunity, issued by the National Cancer Institute (NCI) at NIH, supports investigator-initiated Program Project (P01) applications in any area of cancer research. The P01 mechanism is designed for integrated, collaborative research programs involving multiple independent investigators working toward a unifying scientific goal. Each application must include at least three interrelated research projects and an administrative core, with the option to include shared resource cores if needed. Projects may span basic, translational, clinical, or population-based research, and must collectively address a central theme or objective in cancer biology, prevention, diagnosis, treatment, or control. Clinical trials are permitted but not required.


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