[National Institutes of Health](https://www.nih.gov)

November 3, 2025 (anticipated)

U01 cooperative agreement; award size and duration not yet specified.

Supports innovative, collaborative research on immune mechanisms and regulation at mucosal surfaces of the respiratory, gastrointestinal, and urogenital tracts.

This is a forecasted opportunity; applications are not yet being accepted.

--- ## Description The National Institute of Allergy and Infectious Diseases (NIAID), part of the NIH, intends to issue a Notice of Funding Opportunity (NOFO) for the Mucosal Immunology Studies Team (MIST) program. This initiative will support a cooperative research group focused on advancing the understanding of immune mechanisms and regulation at mucosal surfaces, specifically in the respiratory, gastrointestinal, and urogenital tracts. The primary goal is to foster groundbreaking research by encouraging new ideas, approaches, and technologies that address challenging questions in mucosal immunology. The program will utilize the U01 cooperative agreement mechanism and will emphasize collaborative investigations. This is a forecasted opportunity; the official NOFO has not yet been released. The notice is intended to give potential applicants time to develop collaborations and prepare responsive projects. --- ## Due Dates - Anticipated application due date: **November 3, 2025** - Applications are **not yet being accepted**; this is an advance notice. --- ## Funding Amount - Funding mechanism: **U01 Cooperative Agreement** - Award size and duration: **To be specified in the forthcoming NOFO** - Typical U01 awards support multi-year, collaborative research projects, but specific details for this opportunity are not yet available. --- ## Eligibility Eligible applicants are expected to include: - State governments - County governments - Independent school districts - Public and State controlled institutions of higher education - Native American tribal governments (Federally recognized) - Public housing authorities/Indian housing authorities - Native American tribal organizations (other than Federally recognized tribal governments) - Nonprofits with 501(c)(3) status (other than institutions of higher education) - Private institutions of higher education - For-profit organizations (other than small businesses) - Small businesses Investigators with expertise in mucosal immunology and those interested in collaborative research are especially encouraged to consider applying. --- ## Application Process - The official NOFO will be published at a later date. - This advance notice is to allow time for the development of collaborations and project planning. - Monitor the [NIH Grants Guide](https://grants.nih.gov) for the official announcement and application instructions. --- ## Additional Information - Clinical trials are **not allowed** under this opportunity. - The program is designed to support basic research; translational or clinical studies are not the focus. - Collaborative, multi-disciplinary projects are encouraged. --- ## External Links - [NIH Funder Home Page](https://www.nih.gov) - [NIAID Home Page](https://www.niaid.nih.gov) - [NIH Grants Guide](https://grants.nih.gov) - [Forecasted Opportunity Notice (if available)](https://grants.nih.gov/grants/guide/notice-files/NOT-AI-25-031.html) --- ## Contact Information | Contact Type | Details | |--------------|---------| | NIH Main Line | 301-496-4000 | | NIH Contact Page | [Contact NIH](https://www.nih.gov/about-nih/contact-nih) | ---

Mucosal Immunology Studies Team (MIST) (U01 Clinical Trial Not Allowed)

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