Description

The NBDF-Sanofi Career Development Award is administered by the National Bleeding Disorders Foundation and sponsored by Sanofi. It supports investigators committed to bleeding disorders research, with a preference for those at the assistant professor level or above. The program especially encourages innovative technologies and therapies, supporting studies at subcellular, cellular, animal, and human or patient levels.

Research priorities include hematopoietic, liver, or stem-cell approaches to gene transfer in hemophilia; genetic and immunologic mechanisms of inhibitor development; and genotype/phenotype relationships affecting inhibitor susceptibility. Other interests include less immunogenic replacement factors and gene therapies, more effective and longer-lived clotting factor proteins, small orally delivered biologically active molecules, improved protein delivery systems, and functional assays that validate gene therapy and alternative treatments.