Feasibility Clinical Trials of Mind and Body Interventions for NCCIH High Priority Research Topics (R34 Clinical Trial Required)
Supporting feasibility trials of mind and body interventions for high-priority health conditions to inform future clinical trials for enhanced public health impact.
Funder: National Institutes of Health
Due Dates: November 17, 2026 (Closing date for applications)
Funding Amounts: Up to $450,000 in direct costs over 3 years, with no more than $225,000 annually
Summary: Supports feasibility clinical trials of mind and body interventions that provide essential information for a subsequent full-scale trial.
Key Information: Clinical trials are required; efficacy testing, effect-size estimation, waitlist controls, and cancer prevention or treatment trials are nonresponsive.
Description
The National Center for Complementary and Integrative Health (NCCIH), part of NIH, administers this R34 planning grant for feasibility clinical trials of complementary and integrative health approaches with physical and/or psychological therapeutic inputs. The program supports research needed to design a subsequent efficacy, effectiveness, pragmatic, or dissemination and implementation trial with potential for significant public health impact.
Projects may refine interventions, adapt them to new populations or settings, assess recruitment and retention, test intervention delivery, or examine acceptability and adherence to comparison conditions. Applications must explain why the feasibility work is scientifically necessary and describe the planned future trial. Duplicative feasibility studies involving similar interventions and populations are lower programmatic priority.
