NCCIH Multi-Site Feasibility Clinical Trials of Mind and Body Interventions (R01 Clinical Trial Required)
This grant supports multi-site feasibility clinical trials of mind and body interventions to gather necessary data for future large-scale trials in high-priority health areas.
Funder: National Institutes of Health
Due Dates: November 17, 2026 (Closing date for applications)
Funding Amounts: $350,000 award ceiling listed on Grants.gov; recommended duration up to 3 years (5-year maximum)
Summary: Supports multi-site feasibility clinical trials of mind and body interventions needed to plan subsequent fully powered trials.
Key Information: Requires prior single-site feasibility evidence and at least two geographically distinct recruitment sites with nonoverlapping patient populations.
Description
The National Center for Complementary and Integrative Health (NCCIH) supports investigator-initiated R01 clinical trials of complementary and integrative health approaches with physical or psychological therapeutic inputs. This opportunity funds multi-site feasibility research that supplies scientifically necessary information for a subsequent fully powered efficacy, effectiveness, pragmatic, or dissemination and implementation trial.
Projects should resolve remaining uncertainties about recruitment, randomization, retention, intervention fidelity, adherence, or consistent data collection across sites. They may also assess protocolized multi-component interventions, comparison conditions, or strategies for integrating mind and body approaches into health care systems. Applicants must describe the future trial and explain how the feasibility study will inform its design. This is not support for initial single-site feasibility testing or for testing clinical efficacy.
