[National Institutes of Health](https://www.nih.gov)

October 2026 (Full application deadline, projected)

Up to $700,000 per award; 4 awards expected; duration and total program funding not specified.

Supports collaborative research to build a multimodal inventory of neural cell ensembles altered by addictive substances, integrating cell-level data and advancing understanding of addiction mechanisms.

--- ## Description The National Institute on Drug Abuse (NIDA), part of the National Institutes of Health, anticipates supporting the expansion of the NExUS Collaboratory. The program aims to build a comprehensive knowledgebase of neural cell populations and computations affected by substance use, focusing on neurobehavioral states characteristic of addiction or resilience. Funded projects will: - Collect and share detailed datasets on neural cell populations responsive to substance-related experiences. - Integrate cell-resolved activity data with modalities such as molecular identity, epigenetic state, morphology, spatial localization, and connectivity. - Develop scalable tools for analyzing and visualizing ensemble composition and geometry. - Test and inform models of how cells or motifs are recruited into neural coding ensembles. - Foster coordination and synergy among NExUS and other cell atlasing initiatives, including outreach, data standards, analytics, and reference taxonomies. The funding mechanism is a Cooperative Agreement, emphasizing close collaboration with NIDA program staff. --- ## Due Dates - October 2026 (anticipated full application deadline) *All dates are projected based on the annual cycle; check the program page for updates.* --- ## Funding Amount - Maximum award: $700,000 per project - Expected number of awards: 4 - Total program funding: Not specified - Project duration: Not specified Cost sharing or matching is not required. --- ## Eligibility Eligible applicants include: - State, county, city, or township governments - Special district governments - Independent school districts - Public and private institutions of higher education - Native American tribal governments (federally recognized and other) - Public housing authorities/Indian housing authorities - Nonprofits (with or without 501(c)(3) status, excluding institutions of higher education) - For-profit organizations (including small businesses) - U.S. territories or possessions - Faith-based or community-based organizations - Regional organizations - Eligible agencies of the federal government - Non-domestic (non-U.S.) entities (foreign institutions) See the opportunity listing for the most complete and up-to-date eligibility details. --- ## Application Process - Full applications are anticipated to be due in October 2026. - Applications should address all program objectives, including data collection, integration, tool development, and collaboration. - Prepare to coordinate with NIDA program staff due to the Cooperative Agreement mechanism. - Refer to the [official opportunity listing](https://www.grants.gov/search-results-detail/360562) on Grants.gov for updates, instructions, and required documents. --- ## Additional Information - This is a forecasted opportunity; details may change when the official Notice of Funding Opportunity is published. - The program is designed to encourage data sharing, tool development, and integration across multiple research groups and modalities. - Projects that enhance synergies within the NExUS network and with other cell atlasing efforts are strongly encouraged. --- ## External Links - [NIH Funder Home Page](https://www.nih.gov) - [Official Grants.gov Opportunity Listing](https://www.grants.gov/search-results-detail/360562) - [NIH Contact Page](https://www.nih.gov/about-nih/contact-nih) --- ## Contact Information | Contact | Email | Description | |----------------------------------|--------------------------------------|------------------------------------------------| | Integrative Neuroscience Branch Program Staff | [INBranch_NIDA@nih.gov](mailto:INBranch_NIDA@nih.gov) | Primary program contact for inquiries | | NIH Main Line | 301-496-4000 | NIH general information |

Neural Ensembles & Used Substances (NExUS) Collaboratory: Building a Multimodal Inventory of Cell Ensembles Encoding the Effects of Addictive Substances

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