Funder: National Institutes of Health

Due Dates: January 3, 2025 (Earliest submission) | February 5, 2025 (New) | March 5, 2025 (Renewal/Resubmission/Revision) | June 5, 2025 (New) | July 5, 2025 (Renewal/Resubmission/Revision) | October 5, 2025 (New) | November 5, 2025 (Renewal/Resubmission/Revision) | January 28, 2026 (Final closing date)

Funding Amounts: No budget limit; project period up to 5 years; budgets must reflect actual project needs.

Summary: Supports high-risk, multi-center observational studies (not clinical trials) relevant to NIDDK’s mission; planning must be complete before application.

Key Information: Clinical trials are not allowed; contact NIDDK staff early to confirm project fit and eligibility.