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    Advancing HIV/AIDS Research within the Mission of the NIDCD (R21 Clinical Trial Optional)

    Funding to advance HIV/AIDS research in hearing, balance, taste, smell, voice, speech, and language within NIDCD's mission, prioritizing OAR's research areas.

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    Funder: National Institutes of Health

    Due Dates: May 7, 2025 (AIDS) | September 7, 2025 (AIDS) | January 7, 2026 (AIDS) | May 7, 2026 (AIDS) | June 16, 2026 (New) | July 16, 2026 (Renewal/Resubmission/Revision) | October 16, 2026 (New) | November 16, 2026 (Renewal/Resubmission/Revision) | February 16, 2027 (New) | March 16, 2027 (Renewal/Resubmission/Revision) | June 16, 2027 (New) | July 16, 2027 (Renewal/Resubmission/Revision) | October 16, 2027 (New) | November 16, 2027 (Renewal/Resubmission/Revision)

    Funding Amounts: Up to $275,000 in direct costs over 2 years; no more than $200,000 in any single year.

    Summary: Supports exploratory/developmental HIV/AIDS research in hearing, balance, taste, smell, voice, speech, and language within the NIDCD mission, including low-risk clinical trials.

    Key Information: Only low-risk clinical trials are supported; see program notice for definition and restrictions.


    Description

    This funding opportunity seeks to stimulate HIV/AIDS research in scientific areas aligned with the National Institute on Deafness and Other Communication Disorders (NIDCD). Projects must address high-priority HIV/AIDS research topics as defined by the NIH Office of AIDS Research (OAR), specifically in the domains of hearing, balance, taste, smell, voice, speech, and language. The program supports hypothesis-driven epidemiological, basic, translational, and clinical research, emphasizing the impact of HIV/AIDS on communication disorders and related comorbidities.

    Research may include:

    • Studies on the effects of HIV infection or treatment on communication functions.
    • Identification and mitigation of adverse effects from HIV treatments on sensory and communication processes.
    • Pathophysiological investigations of comorbid communication disorders in people living with HIV (PLWH).
    • Development of prevention or treatment strategies for communication disorders in PLWH.

    Only low-risk clinical trials are eligible under this notice. Multidisciplinary collaborations and leveraging of existing HIV/AIDS cohorts or clinical trial infrastructure are encouraged.


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