Funder: National Institutes of Health

Due Dates: May 6, 2025 (Letter of Intent) | June 5, 2025 (New) | July 5, 2025 (Renewal/Resubmission/Revision) | October 5, 2025 (New) | November 5, 2025 (Renewal/Resubmission/Revision) | Additional cycles through 2026

Funding Amounts: No budget limit; project period up to 3 years; budgets must reflect actual needs.

Summary: Supports discovery research to develop and validate assays for identifying small molecules as chemical probes or therapeutic leads for cancer biology—clinical trials are not allowed.

Key Information: Contact NCI program staff if requesting $500,000 or more in direct costs in any year; foreign and domestic applicants eligible; data sharing to PubChem is expected.