Limited Competition: Basic Instrumentation Grant (BIG) Program (S10 Clinical Trial Not Allowed)
The BIG Program supports NIH-funded groups to buy specialized instruments up to $350,000, open to new applicants without recent S10 funding over $500,000.
Funder: National Institutes of Health
Due Dates: June 2, 2025 | June 1, 2026 | June 1, 2027 (new, renewal, resubmission)
Funding Amounts: $25,000 minimum; up to $350,000 maximum for a single instrument; one-year award
Summary: Supports purchase of a single, new, specialized research instrument for NIH-funded user groups at institutions without recent large S10 instrumentation awards.
Key Information: Limited to institutions that have not received $500,001+ in S10 funding in the preceding 3 federal fiscal years; only one application per institution per cycle.
Description
This opportunity provides funding for the purchase of a single, new, costly, specialized, commercially available research instrument or integrated instrumentation system. The program is designed to broaden access to modern technologies for NIH-funded investigators at institutions that have not recently received substantial S10 instrumentation funding. The instrument must be dedicated to research use and integrated into a core facility or shared laboratory space to maximize institutional and regional impact.
The program specifically targets institutions that are not major recipients of NIH research funding, including those in Institutional Development Award (IDeA) states and those serving diverse populations. The goal is to enhance research capabilities, stimulate new collaborations, and increase overall research competitiveness.
