Funder: National Institutes of Health
Due Dates: June 15, 2025 (Letter of Intent) | July 15, 2025 (Application) | August 19, 2025 (AIDS) | January 15, 2026 | July 15, 2026 | January 15, 2027 | July 15, 2027 | See full schedule for additional cycles through August 2027
Funding Amounts: Budgets are not limited but typically up to $500,000/year (Phase I, max 2 years) and $1,500,000/year (Phase II, max 3 years); total project period up to 5 years.
Summary: Supports small businesses in developing biologic-based therapies for nervous system disorders, from lead optimization through Phase 1 clinical trials.
Key Information: Only U.S. small businesses are eligible; projects must focus on biologics (not small molecules); NIH provides access to contract research resources and consultants.