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    Neuromodulation/Neurostimulation Device Development for Mental Health Applications (R21 Clinical Trial Not Allowed)

    This grant supports developing advanced brain stimulation devices for treating mental health disorders, focusing on novel techniques and significant improvements to existing FDA-approved devices.

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    Funder: National Institutes of Health

    Due Dates: June 16, 2025 (New) | July 16, 2025 (Renewal/Resubmission/Revision) | October 16, 2025 (New) | November 16, 2025 (Renewal/Resubmission/Revision) | February 16, 2026 (New) | March 16, 2026 (Renewal/Resubmission/Revision) | June 16, 2026 (New) | July 16, 2026 (Renewal/Resubmission/Revision) | October 16, 2026 (New) | November 16, 2026 (Renewal/Resubmission/Revision) | February 16, 2027 (New) | March 16, 2027 (Renewal/Resubmission/Revision) | June 16, 2027 (New) | July 16, 2027 (Renewal/Resubmission/Revision) | October 16, 2027 (New) | November 16, 2027 (Renewal/Resubmission/Revision)

    Funding Amounts: Up to $275,000 direct costs over 2 years (no more than $200,000 in any single year); project period max 2 years.

    Summary: Supports development of next-generation brain stimulation devices for mental health disorders, emphasizing novel techniques and significant hardware/software advances beyond incremental updates.

    Key Information: Clinical trials are not allowed; applications must be submitted by multidisciplinary teams.


    Description

    This opportunity from the National Institutes of Health (NIH), specifically the National Institute of Mental Health (NIMH), funds exploratory and developmental research (R21 mechanism) to develop innovative brain stimulation (neuromodulation/neurostimulation) devices for mental health applications. The focus is on either creating novel devices or making significant, non-incremental hardware/software improvements to existing FDA-approved or cleared devices. The goal is to enable new or substantially improved approaches for treating mental health disorders, moving beyond current electrical/magnetic stimulation methods to achieve greater spatiotemporal precision, multi-focal and closed-loop capabilities, and other transformative advances.


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