NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)
The NIH, CDC and FDA Small Business Innovation Research Grant helps US small businesses develop and commercialize cutting-edge health technologies, from early feasibility through advanced research.
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Funder: National Institutes of Health
Due Dates: April 5, 2027
Funding Amounts: Award size and duration vary by project; no explicit ceiling or floor listed—see program details.
Summary: Supports US small businesses in developing and commercializing innovative health-related technologies, from feasibility studies through research and development.
Key Information: Only US small business concerns (SBCs) as defined by SBA are eligible.
Description
This opportunity enables US small businesses to advance scientific innovations toward commercialization in the health sector. The program, administered by the National Institutes of Health (NIH) in partnership with the CDC and FDA, supports projects ranging from initial feasibility studies (Phase I) to full research and development (Phase II). The goal is to accelerate the translation of promising biomedical and health-related technologies into market-ready solutions addressing public health needs.
