Funder: National Institutes of Health
Due Dates: May 28, 2025 | January 27, 2026 (New, Renewal, Resubmission, Revision)
Funding Amounts: Up to $1.5M direct costs/year (most awards $700k–$900k/year); 5 years; optional $250k/year for ESI development (years 2–5)
Summary: Supports highly integrated teams of 3–6 PIs to address ambitious, synergistic research questions within the NIGMS mission; not for resource, technology, or clinical efficacy projects.
Key Information: Limited to two applications per institution per round; clinical trials for safety/efficacy (Phases I–III) are not allowed; prior NIGMS consultation strongly encouraged.