Competing Revisions to Existing NIH Single Project Research Grants and Cooperative Agreements (Clinical Trial Optional)
NIH offers funding for expanding existing projects or programs under specific criteria through Competing Revisions to NIH single project research grants and cooperative agreements without requiring clinical trials.
Funder: National Institutes of Health
Due Dates: See Notice of Special Interest (NOSI) for deadlines | Final expiration: November 24, 2026
Funding Amounts: Budget and duration set by NOSI; typically up to 2 years within the parent award period; no fixed ceiling
Summary: Supports competitive revision applications to expand the scope of active NIH single project research grants or cooperative agreements in response to a published NOSI.
Key Information: Only current NIH awardees may apply, and applications must respond to a specific NOSI from an NIH Institute or Center.
Description
This opportunity allows current NIH award recipients to apply for additional funding to expand the scope of their existing single project research grants or cooperative agreements. These "competing revisions" (formerly known as competitive supplements) are intended to support new research aims or activities that build upon the parent award, in alignment with priorities outlined in a Notice of Special Interest (NOSI) published by an NIH Institute, Center, or Office (ICO). Both clinical trial and non-clinical trial projects are eligible, depending on the NOSI.
Applications must be directly responsive to a published NOSI referencing this funding announcement. The parent award must have at least two years remaining in its project period at the time of application.
