Description

The National Center for Advancing Translational Sciences (NCATS) at NIH invites applications for projects focused on the development of highly innovative, early-stage technologies that can address significant challenges in translational science, especially those relevant to therapeutic development. This program is designed to support investigator-initiated, proof-of-concept, and exploratory technology development studies that are high-risk but have the potential for transformative impact. The goal is to catalyze new approaches or extend current technologies in ways that could significantly improve the efficiency of the therapeutic development pipeline, ultimately leading to more treatments reaching patients more quickly.

Projects should be disease-agnostic and applicable to broader use in translational research, with an emphasis on platform-based approaches rather than incremental advances or disease-specific solutions. This opportunity is not intended for clinical trials or studies focused on a single disease mechanism.