Data Coordinating Center for Multi-Site Investigator-Initiated Clinical Trials (Collaborative U24 Clinical Trial Required)
NHLBI seeks a Data Coordinating Center to manage data and provide statistical support for multi-site clinical trials, requiring collaboration with a Clinical Coordinating Center.
Funder: National Institutes of Health
Due Dates: November 2, 2028
Funding Amounts: Not specified; cooperative agreement mechanism; see NOFO for details.
Summary: Supports a Data Coordinating Center for investigator-initiated multi-site clinical trials relevant to NHLBI’s mission.
Key Information: DCC and collaborating CCC applications must be submitted together on the same due date.
Description
This opportunity funds a Data Coordinating Center (DCC) to support investigator-initiated, multi-site clinical trials—including efficacy, comparative effectiveness, pragmatic, and/or implementation research trials—aligned with the research mission of the National Heart, Lung, and Blood Institute (NHLBI). The DCC is expected to provide comprehensive project coordination, administration, data management, and biostatistical support. Innovative trial designs (platform, adaptive, Bayesian) are encouraged, and projects can address therapeutic, behavioral, or prevention strategies. The DCC will also work closely with a collaborating Clinical Coordinating Center (CCC) to implement the clinical trial’s community engagement plan. Both DCC and CCC applications must be submitted in parallel for consideration.
