Support research in implementing effective health interventions, especially in underrepresented communities, while also exploring the cessation of ineffective practices and improving research methods.
Funder: National Institutes of Health
Due Dates: November 5, 2026 (Renewal/resubmission/revision) | February 5, 2027 (New) | March 5, 2027 (Renewal/resubmission/revision) | June 5, 2027 (New) | July 5, 2027 (Renewal/resubmission/revision) | October 5, 2027 (New) | November 5, 2027 (Renewal/resubmission/revision) | January 7, 2028 (Closing date)
Funding Amounts: Budgets are not capped and must reflect project needs; maximum project period of 5 years; no cost sharing required.
Summary: Supports research on strategies to disseminate, implement, sustain, scale, or de-implement health interventions and advance implementation research methods.
Key Information: Foreign organizations are eligible, but applications involving foreign subawards or subcontracts will not be considered for funding.
This NIH R01 program supports studies identifying, developing, or testing strategies to overcome barriers to adopting, adapting, integrating, sustaining, scaling, and spreading evidence-based health interventions. These include practices, programs, tools, treatments, guidelines, and policies in public health, clinical practice, and community settings. Projects must fit the mission of at least one participating NIH Institute or Center.
The program also encourages research on de-implementing ineffective, unproven, low-value, or harmful practices; improving dissemination and implementation methods and measures; and re-implementing evidence-based services disrupted by disasters. Supported designs include observational, experimental, quasi-experimental, and simulation studies. Research may examine implementation outcomes, costs, mechanisms, contextual influences, and unintended consequences. Clinical trials are optional, subject to Institute-specific restrictions; intervention efficacy trials are not responsive.