Funder: National Institutes of Health
Due Dates: November 16, 2026 (Resubmission) | February 16, 2027 (New) | March 16, 2027 (Resubmission) | June 16, 2027 (New) | July 16, 2027 (Resubmission) | October 16, 2027 (New) | November 16, 2027 (Resubmission) | January 7, 2028 (Final closing)
Funding Amounts: Up to $275,000 in direct costs over 2 years, with no more than $200,000 in one year
Summary: Supports exploratory and developmental research on strategies to disseminate, implement, sustain, or de-implement health interventions.
Key Information: Projects must fit a participating NIH Institute/Center mission; efficacy trials and testing therapies or devices are nonresponsive.
Description
This NIH R21 opportunity supports early-stage research identifying, developing, or testing strategies to overcome barriers to adopting, adapting, integrating, sustaining, scaling up, and spreading evidence-based health interventions. It also supports research on discontinuing ineffective, unproven, low-value, or harmful practices and re-implementing evidence-based services disrupted by disasters.
The program encourages advances in dissemination and implementation methods, measures, theories, and frameworks. Relevant work includes pilot implementation strategies, economic evaluations, policy implementation, secondary-data analyses, and qualitative or modeling methods. Observational, experimental, quasi-experimental, and simulation designs are supported. The goal is to bridge research, practice, and policy by understanding both whether implementation strategies work and how, why, for whom, and under what conditions they work.
