Early Stage Investigator HIV/AIDS Research Using Nonhuman Primate (NHP) Models (R21 Clinical Trial Not Allowed)
Supporting Early Stage Investigators for HIV/AIDS research using Nonhuman Primate models to advance preclinical research and competitiveness for further funding.
This grant is no longer accepting proposals
National Institutes of Health has archived this opportunity.
Funder: National Institutes of Health
Due Dates: May 7, 2025 (AIDS) | September 7, 2025 (AIDS)
Funding Amounts: Up to $200,000 direct costs/year; max $400,000 direct costs over 2 years; project period up to 2 years.
Summary: Supports Early Stage Investigators conducting preclinical HIV/AIDS research using nonhuman primate models to foster independence and competitiveness for future funding.
Key Information: Clinical trials are not allowed; applicants must be within 10 years of terminal degree and have at least 2 years postdoctoral experience.
Description
This funding opportunity supports Early Stage Investigators (ESIs) in conducting preclinical HIV/AIDS research using nonhuman primate (NHP) models. The goal is to provide ESIs with the resources and independence needed to develop new research directions and become competitive for future NIH funding (e.g., R01 grants). Projects must use NHPs as preclinical models for HIV/AIDS research and align with the NIH Strategic Plan for HIV and HIV-Related Research, including priorities such as reducing HIV incidence, developing next-generation therapies, pursuing HIV cure research, addressing comorbidities and coinfections, and advancing cross-cutting research areas.
Research topics of interest include, but are not limited to:
- Vaccine and non-vaccine prevention strategies (e.g., microbicides, monoclonal antibodies)
- Antiretroviral therapies and combination treatments
- Identification and targeting of viral reservoirs
- Biomarker discovery for viral remission or reactivation
- Impact of comorbidities and coinfections on HIV/SIV/SHIV
- Imaging and tracking of virus and immune responses
The National Institute of Mental Health (NIMH) is particularly interested in CNS-related HIV research, including mechanisms of HIV-1 persistence/latency in the CNS and biomarker development for CNS disease.
