NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Not Allowed)
NIH's R21 grant funds high-risk, early-stage research with potential for breakthroughs in biomedical, behavioral, or clinical fields, excluding clinical trials.
Funder: National Institutes of Health
Due Dates: February 16, 2025 | June 16, 2025 | October 16, 2025 | February 16, 2026 | June 16, 2026 | October 16, 2026 | February 16, 2027 | June 16, 2027 | October 16, 2027 | January 7, 2028 (final)
Funding Amounts: Up to $275,000 direct costs over 2 years; no more than $200,000 in any single year.
Summary: Supports early-stage exploratory and developmental research projects in biomedical, behavioral, or clinical research; clinical trials are not allowed.
Key Information: Only non-clinical trial proposals are accepted; check IC participation before applying.
Description
This opportunity provides support for exploratory and developmental research projects in the early and conceptual stages. The program is designed to encourage novel scientific ideas, model systems, tools, agents, targets, and technologies that have the potential to substantially advance biomedical, behavioral, or clinical research. Projects may involve considerable risk but could lead to breakthroughs or the development of innovative techniques, methodologies, or applications that have significant impact. This funding announcement does not accept applications proposing clinical trials.
Participating NIH Institutes and Centers (ICs) support a broad range of research areas, but not all ICs participate in this parent announcement. Applicants should confirm that their research area aligns with the mission and interests of a participating IC before applying.
