The NIDDK Disorders of Gastrointestinal Interoception Consortium Clinical Centers (DGIC)
This grant funds a consortium to study and improve understanding of gastrointestinal disorders linked to impaired interoception, expanding research beyond gastroparesis to include other adult and pediatric GI conditions.
Funder: National Institutes of Health (NIH)
Due Dates: November 1, 2026 (Estimated, Forecasted)
Funding Amounts: Estimated total program funding $3,000,000; up to 6 awards; cooperative agreement
Summary: Supports multidisciplinary clinical research centers focused on adult and pediatric gastrointestinal disorders involving impaired interoceptive processing, expanding beyond gastroparesis.
Key Information: This is a forecasted opportunity; dates and details may change.
Description
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the NIH, is planning to fund up to six Clinical Research Centers as part of the Disorders of Gastrointestinal Interoception Consortium (DGIC). This initiative builds on the work of the NIDDK Gastroparesis Consortium (GpCRC), expanding its focus from gastroparesis to a broader range of gastrointestinal (GI) disorders linked to impaired interoceptive processing in both adults and children.
The DGIC will support multidisciplinary research to:
- Elucidate mechanisms connecting GI function (e.g., motility) to clinical symptoms.
- Identify biomarkers for disease and treatment response.
- Leverage advanced technologies to discover novel therapeutic targets.
- Enable future clinical trials for GI disorders involving altered interoception, with an emphasis on overlapping symptoms like nausea, vomiting, and altered bowel habits.
The initiative aims to foster collaboration and data sharing, including integration with a central data repository and coordination with a Scientific Data Research Center (SDRC).
