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    Forecast to Publish a Funding Opportunity Announcement for Copy of Integrative Neuroscience Initiative on Alcoholism (INIA) Consortia Administrative Resource Core (U24) (Clinical Trial Optional)

    NIAAA plans to fund two research groups studying how alcohol affects the brain and body, seeking to identify ways to prevent and treat alcohol use disorder.

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    National Institutes of Health has archived this opportunity.

    Funder: National Institutes of Health

    Due Dates: May 1, 2026 (anticipated NOFO release; applications not yet solicited)

    Funding Amounts: Not yet specified; supports two multisite consortia via U24 cooperative agreements.

    Summary: NIH plans to renew funding for collaborative consortia studying brain-body mechanisms underlying excessive alcohol use and Alcohol Use Disorder.

    Key Information: This is a forecasted opportunity; no applications are being accepted yet.


    Description

    The National Institute on Alcohol Abuse and Alcoholism (NIAAA) at NIH is forecasting a Funding Opportunity Announcement (FOA) to renew the Integrative Neuroscience Initiative on Alcoholism (INIA). This initiative will support two collaborative research consortia, each with administrative and resource cores, to investigate the brain-body homeostatic dysregulation that promotes and perpetuates excessive alcohol consumption and Alcohol Use Disorder (AUD).

    The initiative encourages hypothesis-driven, multisite research on the interactions between alcohol and other causal influences, focusing on the progression from initial alcohol exposure to pathological drinking. The goal is to identify translatable markers and mechanisms that can inform prevention and intervention strategies for AUD and related chronic conditions.

    Key features include:

    • Adaptation of advanced tools and technologies from the BRAIN Initiative, NIH Common Fund, and other sources.
    • Multiscale analysis of brain structure and function, from microcircuitry to whole-brain networks, including peripheral influences.
    • Emphasis on standardization, rigor, and reproducibility across consortia, including shared resources and experimental protocols.
    • Cross-species translational approaches.

    This opportunity will use the U24 cooperative agreement mechanism. The notice is provided in advance to allow potential applicants time to develop collaborations and responsive projects.


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