Funder: National Institutes of Health (NIH)
Due Dates: September 26, 2025 | January 27, 2026 | May 27, 2026 | September 28, 2026 | January 26, 2027 | May 26, 2027 | September 28, 2027 | January 26, 2028 | May 26, 2028 | August 25, 2028 (final)
Funding Amounts: No budget limit, but budgets must reflect actual needs; max project period 5 years.
Summary: Supports early stage investigators proposing innovative, human-based basic experimental studies representing a change in research direction, with no preliminary data allowed.
Key Information: Preliminary data are not allowed; all PD/PIs must be ESIs and the proposed project must represent a new research direction for each.