NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Required)
The NIH Pathway to Independence Award supports postdocs transitioning to independent investigators for NIH-funded research careers.
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Funder: National Institutes of Health
Due Dates: November 12, 2026 (Resubmission/revision) | February 12, 2027 (New) | March 12, 2027 (Resubmission/revision) | May 7, 2027 (Closing date)
Funding Amounts: Up to 5 years total; R00 phase up to $249,000 annually for 3 years; K99 support follows Institute/Center limits
Summary: Supports mentored postdoctoral researchers transitioning to independent faculty careers while leading an independent clinical trial, feasibility study, or ancillary clinical trial.
Key Information: Candidates generally must have no more than 4 years of postdoctoral research experience and need at least 12 additional months of mentoring.
Description
The NIH Pathway to Independence Award (K99/R00) helps researchers with clinical or research doctorates move from mentored postdoctoral positions to independent, tenure-track or equivalent faculty positions. It combines mentored research and career development with independent research support, helping awardees establish programs competitive for subsequent independent funding.
This announcement, PA-24-193, specifically supports candidates serving as lead investigators of independent clinical trials, clinical trial feasibility studies, or separate ancillary clinical trials. Research must fit a participating NIH Institute or Center’s mission. Candidates not planning an independent trial, including those gaining experience in another investigator’s trial, must use the companion announcement, PA-24-194.
