Pilot Health Services and Economic Research on the Treatment of Drug, Alcohol, and Tobacco Use Disorders (R34 Clinical Trial Optional)
Funding available for pilot research to improve access and effectiveness of treatments for drug, alcohol, and tobacco use disorders, including comorbid conditions.
Funder: National Institutes of Health
Due Dates: June 16, 2025 (New) | July 16, 2025 (Renewal/Resubmission/Revision) | September 7, 2025 (AIDS) | October 16, 2025 (New) | November 16, 2025 (Renewal/Resubmission/Revision) | January 7, 2026 (AIDS) | February 16, 2026 (New) | March 16, 2026 (Renewal/Resubmission/Revision) | May 7, 2026 (AIDS) | June 16, 2026 (New) | July 16, 2026 (Renewal/Resubmission/Revision) | September 7, 2026 (AIDS) | October 16, 2026 (New) | November 16, 2026 (Renewal/Resubmission/Revision) | January 7, 2027 (AIDS) | February 16, 2027 (New) | March 16, 2027 (Renewal/Resubmission/Revision) | May 7, 2027 (AIDS)
Funding Amounts: Up to $450,000 direct costs over 3 years; no more than $225,000 in any single year; project period up to 3 years.
Summary: Supports pilot research to prepare for larger-scale studies on improving access, quality, effectiveness, affordability, and utilization of drug, tobacco, or alcohol use disorder treatments and related services, including for comorbid conditions.
Key Information: Applications focused on alcohol use alone are not responsive; both clinical trial and non-trial projects are allowed.
Description
This opportunity, offered by the National Institute on Drug Abuse (NIDA) at NIH, funds pilot and preliminary research to prepare for larger-scale effectiveness trials in health services and economic research related to the treatment of drug, tobacco, or alcohol use disorders (SUDs), including comorbid medical and mental health conditions. The program supports studies that test a wide range of approaches—novel or commonly used but lacking an evidence base—aimed at optimizing access, quality, effectiveness, affordability, and utilization of SUD treatments and related services.
Projects may include pilot testing of interventions, practices, or policies at the provider, organizational, system, or payer level. The mechanism is intended to support feasibility, acceptability, and utility assessments, as well as usual trial preparation activities, to inform subsequent larger-scale (R01-level) effectiveness research.
Note: Applications focused solely on alcohol use disorder are not responsive.
