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    Pilot Studies of Biological, Behavioral and Social Mechanisms Contributing to HIV Pathogenesis Within the Mission of NIDDK (R21 Clinical Trial Not Allowed)

    Research grant for studying biological, behavioral, and social factors impacting HIV pathogenesis within NIDDK's mission and NIH priorities.

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    Funder: National Institutes of Health

    Due Dates: May 7, 2025 (AIDS) | September 7, 2025 (AIDS) | January 7, 2026 (AIDS) | May 7, 2026 (AIDS) | June 16, 2026 (non-AIDS) | October 16, 2026 (non-AIDS) | February 16, 2027 (non-AIDS) | June 16, 2027 (non-AIDS) | October 16, 2027 (non-AIDS) | November 16, 2027 (non-AIDS)

    Funding Amounts: Up to $275,000 direct costs over 2 years; no more than $200,000 in any single year; project period up to 2 years.

    Summary: Supports innovative basic and translational pilot research on biological, behavioral, and social mechanisms contributing to HIV pathogenesis within the NIDDK mission.


    Description

    This opportunity supports exploratory and developmental (R21) pilot research projects investigating biological, behavioral, and social mechanisms that contribute to HIV pathogenesis and related comorbidities, coinfections, and complications (CCCs) within the research mission of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Projects should align with NIH HIV/AIDS research priorities, including studies on pathophysiological mechanisms, HIV reservoirs in NIDDK-relevant tissues (e.g., gastrointestinal tract, kidney, adipose tissue, male genital tract), and the impact of social determinants of health (SDoH) on HIV outcomes and viral reservoirs.

    Clinical trials are not allowed under this funding opportunity. Projects may involve human subjects, animal models, non-identifiable biospecimens, and epidemiological or observational research addressing environmental, psychological, behavioral, and social processes relevant to HIV pathogenesis and NIDDK-related diseases.


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