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    NIH Research Project Grant (Parent R01 Basic Experimental Studies with Humans Required)

    NIH grant supports basic science projects with human experiments, focusing on fundamental understanding rather than specific applications.

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    Funder: National Institutes of Health

    Due Dates: February 5, 2025 (New) | March 5, 2025 (Renewal/Resubmission/Revision) | May 7, 2025 (AIDS) | June 5, 2025 (New) | July 5, 2025 (Renewal/Resubmission/Revision) | September 7, 2025 (AIDS) | October 5, 2025 (New) | November 5, 2025 (Renewal/Resubmission/Revision) | January 7, 2026 (AIDS) | February 5, 2026 (New) | March 5, 2026 (Renewal/Resubmission/Revision) | May 7, 2026 (AIDS) | June 5, 2026 (New) | July 5, 2026 (Renewal/Resubmission/Revision) | September 7, 2026 (AIDS) | October 5, 2026 (New) | November 5, 2026 (Renewal/Resubmission/Revision) | January 7, 2027 (AIDS) | February 5, 2027 (New) | March 5, 2027 (Renewal/Resubmission/Revision) | May 7, 2027 (AIDS) | June 5, 2027 (New) | July 5, 2027 (Renewal/Resubmission/Revision) | September 7, 2027 (AIDS) | October 5, 2027 (New) | November 5, 2027 (Renewal/Resubmission/Revision) | January 7, 2028 (AIDS)

    Funding Amounts: No budget limit; budgets must reflect actual needs; maximum project period is 5 years.

    Summary: Supports investigator-initiated basic experimental studies involving humans to advance fundamental understanding of biomedical or behavioral phenomena.


    Description

    This opportunity supports investigator-initiated basic science experimental studies involving humans, specifically those that prospectively assign human participants to conditions and assess biomedical or behavioral outcomes to advance fundamental knowledge, without a specific application toward processes or products. The grant is intended for projects that fall under the NIH definition of a clinical trial and also qualify as basic research. Applicants must align their proposals with the scientific missions of participating NIH Institutes and Centers.

    Studies with a specific application toward processes or products, including mechanistic clinical trials, safety/efficacy studies, or FDA-regulated trials, should apply under other appropriate funding opportunities. This opportunity is designed for research that seeks to understand fundamental aspects of phenomena in humans.


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