NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed)
NIH grant supports specific research projects aligned with NIH Institutes' missions, but excludes clinical trials.
Funder: National Institutes of Health
Due Dates: June 5, 2025 (New) | July 5, 2025 (Renewal/Resubmission/Revision) | September 7, 2025 (AIDS) | October 5, 2025 (New) | November 5, 2025 (Renewal/Resubmission/Revision) | January 7, 2026 (AIDS) | Additional standard NIH due dates through January 7, 2028
Funding Amounts: No budget cap; budgets must reflect actual project needs. Maximum project period: 5 years.
Summary: Supports discrete, investigator-initiated research projects aligned with NIH Institutes’ missions; clinical trials are not allowed.
Key Information: Applicants requesting ≥$500,000 in direct costs in any year must contact NIH at least 6 weeks before submission.
Description
This opportunity supports investigator-initiated research projects in scientific areas that align with the missions of participating NIH Institutes and Centers (ICs). The grant is intended for discrete, specified, and circumscribed projects representing the specific interests and competencies of the investigator(s). Applications proposing clinical trials are not permitted under this announcement.
Projects must be relevant to the programmatic interests of at least one participating NIH IC. Applicants are strongly encouraged to review the IC-specific interests and contacts to ensure alignment and to consult with NIH staff before applying.
